Mesothelium – Definition, Structure and Purpose

Mesothelium

 Definition, Structure and Purpose

 

The mesothelium forms a monolayer of flat squamous-like epithelial cells resting on a very thin basement membrane. Cuboidal mesothelial cells could be seen at the peritoneal side of the diaphragm, the milky spots of the omentum, as well as places of harm overlaying the lymphatic lacunae. The proteins and serosal fluid supply a slick surface for internal organs to slip past one another.

The mesothelium consists of an extensive monolayer of specialized cells (mesothelial cells) that line the entire body’s serous cavities and internal organs. The primary function of these cells would be to create a lubricating fluid that’s discharged between layers, supplying a slick, non adhesive, and surface that is protective to ease motion that is intracoelomic.

Mesothelial cells are presenting cells and are capable of phagocytosis. Also, the secretion of glycosaminoglycans and lubricants may protect the body against disease and tumour dissemination.

This layer was considered to be an easy tissue together with the only function of supplying a slick, non-adhesive protective and surface to ease motion that was filled with fluid. Yet, together with the slow accumulation of information about serosal tissues over time, the mesothelium is recognized as a dynamic cellular membrane that has many important functions. Also, the secretion of molecules, including lubricants and glycosaminoglycans protects tissues from abrasion, but in addition from disease and perhaps tumour dissemination. Mesothelium is, in addition, unlike other epithelial-like surfaces whereas in authentic epithelia, healing happens only at the wound borders as sheets of cells, because healing seems across the denuded surface. Recent research have started to shed light on the mechanisms, although contentious. In the present review, the current grasp of the biology of mesothelial cells and function of the mesothelium as well as the arrangement is discussed, together with recent insights into the mechanisms controlling its repair.

 

Sources:

https://en.wikipedia.org/wiki/Mesothelium

https://www.ncbi.nlm.nih.gov/pubmed/12153683